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Clinical trials for BET inhibitors run ahead of the science
Several cancer clinical trials for small molecule inhibitors of BET bromodomain proteins have been initiated. There is enthusiasm for the anti-proliferative effect of inhibiting BRD4, one of the targets of these inhibitors, which is thought to cooperate with MYC, a long-desired target for cancer the...
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| Publicado no: | Drug Discov Today Technol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5116321/ https://ncbi.nlm.nih.gov/pubmed/27769357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ddtec.2016.06.004 |
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