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Long-Range Control of Renin Gene Expression in Tsukuba Hypertensive Mice
Renin, a rate-limiting enzyme in the renin–angiotensin system, is regulated to maintain blood pressure homeostasis: renin gene expression in the kidney is suppressed in a hypertensive environment. We found that expression of a 15-kb human RENIN (hREN) transgene was aberrantly upregulated (>4.2-fo...
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| Izdano u: | PLoS One |
|---|---|
| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5115840/ https://ncbi.nlm.nih.gov/pubmed/27861631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166974 |
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