Synthetic DNA fragments bearing ICR cis elements become differentially methylated and recapitulate genomic imprinting in transgenic mice

BACKGROUND: Genomic imprinting is governed by allele-specific DNA methylation at imprinting control regions (ICRs), and the mechanism controlling its differential methylation establishment during gametogenesis has been a subject of intensive research interest. However, recent studies have reported t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Epigenetics Chromatin
Päätekijät: Matsuzaki, Hitomi, Okamura, Eiichi, Kuramochi, Daichi, Ushiki, Aki, Hirakawa, Katsuhiko, Fukamizu, Akiyoshi, Tanimoto, Keiji
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2018
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6027785/
https://ncbi.nlm.nih.gov/pubmed/29958543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-018-0207-z
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia