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Identifying Causal Genes at the Multiple Sclerosis Associated Region 6q23 Using Capture Hi-C

BACKGROUND: The chromosomal region 6q23 has been found to be associated with multiple sclerosis (MS) predisposition through genome wide association studies (GWAS). There are four independent single nucleotide polymorphisms (SNPs) associated with MS in this region, which spans around 2.5 Mb. Most GWA...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Martin, Paul, McGovern, Amanda, Massey, Jonathan, Schoenfelder, Stefan, Duffus, Kate, Yarwood, Annie, Barton, Anne, Worthington, Jane, Fraser, Peter, Eyre, Stephen, Orozco, Gisela
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2016
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115837/
https://ncbi.nlm.nih.gov/pubmed/27861577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166923
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