Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23

BACKGROUND: The identification of causal genes from genome-wide association studies (GWAS) is the next important step for the translation of genetic findings into biologically meaningful mechanisms of disease and potential therapeutic targets. Using novel chromatin interaction detection techniques a...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: McGovern, Amanda, Schoenfelder, Stefan, Martin, Paul, Massey, Jonathan, Duffus, Kate, Plant, Darren, Yarwood, Annie, Pratt, Arthur G., Anderson, Amy E., Isaacs, John D., Diboll, Julie, Thalayasingam, Nishanthi, Ospelt, Caroline, Barton, Anne, Worthington, Jane, Fraser, Peter, Eyre, Stephen, Orozco, Gisela
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5088679/
https://ncbi.nlm.nih.gov/pubmed/27799070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1078-x
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