Identifying Causal Genes at the Multiple Sclerosis Associated Region 6q23 Using Capture Hi-C

BACKGROUND: The chromosomal region 6q23 has been found to be associated with multiple sclerosis (MS) predisposition through genome wide association studies (GWAS). There are four independent single nucleotide polymorphisms (SNPs) associated with MS in this region, which spans around 2.5 Mb. Most GWA...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Martin, Paul, McGovern, Amanda, Massey, Jonathan, Schoenfelder, Stefan, Duffus, Kate, Yarwood, Annie, Barton, Anne, Worthington, Jane, Fraser, Peter, Eyre, Stephen, Orozco, Gisela
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115837/
https://ncbi.nlm.nih.gov/pubmed/27861577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166923
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