Cyclooxygenase Isoform Exchange Blocks Brain-Mediated Inflammatory Symptoms

Cyclooxygenase-2 (COX-2) is the main source of inducible prostaglandin E(2) production and mediates inflammatory symptoms including fever, loss of appetite and hyperalgesia. COX-1 is dispensable for fever, anorexia and hyperalgesia but is important for several other functions both under basal condit...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Björk Wilhelms, Daniel, Mirrasekhian, Elahe, Zajdel, Joanna, Kumar Singh, Anand, Engblom, David
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115700/
https://ncbi.nlm.nih.gov/pubmed/27861574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166153
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