Systemic GM-CSF recruits effector T cells into the tumor microenvironment in localized prostate cancer

Granulocytic-macrophage colony-stimulating factor (GM-CSF) is used as an adjuvant in cancer vaccine trials and has the potential to enhance antitumor efficacy with immunotherapy; however, its immunologic effects are not fully understood. Here, we report results from a phase 1 study of neoadjuvant GM...

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Foilsithe in:Cancer Immunol Res
Main Authors: Wei, Xiao X., Chan, Stephen, Kwek, Serena, Lewis, Jera, Dao, Vinh, Zhang, Li, Cooperberg, Matthew R., Ryan, Charles J., Lin, Amy M., Friedlander, Terence W., Rini, Brian, Kane, Christopher, Simko, Jeffry P., Carroll, Peter R., Small, Eric J., Fong, Lawrence
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115633/
https://ncbi.nlm.nih.gov/pubmed/27688020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-16-0042
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