Systemic GM-CSF recruits effector T cells into the tumor microenvironment in localized prostate cancer

Granulocytic-macrophage colony-stimulating factor (GM-CSF) is used as an adjuvant in cancer vaccine trials and has the potential to enhance antitumor efficacy with immunotherapy; however, its immunologic effects are not fully understood. Here, we report results from a phase 1 study of neoadjuvant GM...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Wei, Xiao X., Chan, Stephen, Kwek, Serena, Lewis, Jera, Dao, Vinh, Zhang, Li, Cooperberg, Matthew R., Ryan, Charles J., Lin, Amy M., Friedlander, Terence W., Rini, Brian, Kane, Christopher, Simko, Jeffry P., Carroll, Peter R., Small, Eric J., Fong, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115633/
https://ncbi.nlm.nih.gov/pubmed/27688020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-16-0042
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