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Diversity of antigen-specific responses induced in vivo with CTLA-4 blockade in prostate cancer patients
Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is a surface receptor on activated T cells that delivers an inhibitory signal, serving as an immune checkpoint. Treatment with anti-CTLA-4 antibodies can induce clinical responses to different malignancies, but the nature of the induced antigen-sp...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3448828/ https://ncbi.nlm.nih.gov/pubmed/22956585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201529 |
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