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An aberrant prostate antigen–specific immune response causes prostatitis in mice and is associated with chronic prostatitis in humans

Chronic prostatitis is a common disease of unclear etiology and has no specific treatment. Mice deficient in the expression of the autoimmune regulator (Aire) gene, which are defective in thymic expression of self antigens and central tolerance, develop spontaneous prostatitis. In this study, we fou...

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Detalhes bibliográficos
Main Authors: Hou, Yafei, DeVoss, Jason, Dao, Vinh, Kwek, Serena, Simko, Jeffrey P., McNeel, Douglas G., Anderson, Mark S., Fong, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701875/
https://ncbi.nlm.nih.gov/pubmed/19603556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38332
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