Systemic GM-CSF recruits effector T cells into the tumor microenvironment in localized prostate cancer

Granulocytic-macrophage colony-stimulating factor (GM-CSF) is used as an adjuvant in cancer vaccine trials and has the potential to enhance antitumor efficacy with immunotherapy; however, its immunologic effects are not fully understood. Here, we report results from a phase 1 study of neoadjuvant GM...

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Publicat a:Cancer Immunol Res
Autors principals: Wei, Xiao X., Chan, Stephen, Kwek, Serena, Lewis, Jera, Dao, Vinh, Zhang, Li, Cooperberg, Matthew R., Ryan, Charles J., Lin, Amy M., Friedlander, Terence W., Rini, Brian, Kane, Christopher, Simko, Jeffry P., Carroll, Peter R., Small, Eric J., Fong, Lawrence
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115633/
https://ncbi.nlm.nih.gov/pubmed/27688020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-16-0042
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