MicroRNA let-7, T cells, and patient survival in colorectal cancer

Experimental evidence suggests that the let-7 family of noncoding RNAs suppresses adaptive immune responses, contributing to immune evasion by the tumor. We hypothesized that the amount of let-7a and let-7b expression in colorectal carcinoma might be associated with limited T-lymphocyte infiltrates...

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Publicado en:Cancer Immunol Res
Autores principales: Dou, Ruoxu, Nishihara, Reiko, Cao, Yin, Hamada, Tsuyoshi, Mima, Kosuke, Masuda, Atsuhiro, Masugi, Yohei, Shi, Yan, Gu, Mancang, Li, Wanwan, da Silva, Annacarolina, Nosho, Katsuhiko, Zhang, Xuehong, Meyerhardt, Jeffrey A., Giovannucci, Edward L., Chan, Andrew T., Fuchs, Charles S., Qian, Zhi Rong, Ogino, Shuji
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5115629/
https://ncbi.nlm.nih.gov/pubmed/27737877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-16-0112
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