Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor alpha locus.

Acute promyelocytic leukemias (APLs) are characterized by a reciprocal balanced translocation that involves chromosomes 15 and 17 [t(15;17)]. We report the isolation and characterization of one of the two reciprocal break sites and demonstrate that the chromosome 17 breakpoint lies within the retino...

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Autors principals: Alcalay, M, Zangrilli, D, Pandolfi, P P, Longo, L, Mencarelli, A, Giacomucci, A, Rocchi, M, Biondi, A, Rambaldi, A, Lo Coco, F
Format: Artigo
Idioma:Inglês
Publicat: 1991
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC51149/
https://ncbi.nlm.nih.gov/pubmed/1848017
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