Salinomycin inhibits metastatic colorectal cancer growth and interferes with Wnt/β-catenin signaling in CD133(+) human colorectal cancer cells

BACKGROUND: The polyether antibiotic Salinomycin (Sal) is regarded as an inhibitor of cancer stem cells. Its effectiveness on human colorectal cancer (CRC) cells in vitro has been demonstrated before. The aim of this study was to establish a murine model to investigate the effectiveness of Sal in vi...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Klose, Johannes, Eissele, Jana, Volz, Claudia, Schmitt, Steffen, Ritter, Alina, Ying, Shen, Schmidt, Thomas, Heger, Ulrike, Schneider, Martin, Ulrich, Alexis
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114842/
https://ncbi.nlm.nih.gov/pubmed/27855654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-2879-8
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