Dormant cancer cells accumulate high protoporphyrin IX levels and are sensitive to 5-aminolevulinic acid-based photodynamic therapy

Photodynamic therapy (PDT) and diagnosis (PDD) using 5-aminolevulinic acid (ALA) to drive the production of an intracellular photosensitizer, protoporphyrin IX (PpIX), are in common clinical use. However, the tendency to accumulate PpIX is not well understood. Patients with cancer can develop recurr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Nakayama, Taku, Otsuka, Shimpei, Kobayashi, Tatsuya, Okajima, Hodaka, Matsumoto, Kentaro, Hagiya, Yuichiro, Inoue, Keiji, Shuin, Taro, Nakajima, Motowo, Tanaka, Tohru, Ogura, Shun-ichiro
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114660/
https://ncbi.nlm.nih.gov/pubmed/27857072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36478
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