Dormant cancer cells accumulate high protoporphyrin IX levels and are sensitive to 5-aminolevulinic acid-based photodynamic therapy

Photodynamic therapy (PDT) and diagnosis (PDD) using 5-aminolevulinic acid (ALA) to drive the production of an intracellular photosensitizer, protoporphyrin IX (PpIX), are in common clinical use. However, the tendency to accumulate PpIX is not well understood. Patients with cancer can develop recurr...

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Опубликовано в: :Sci Rep
Главные авторы: Nakayama, Taku, Otsuka, Shimpei, Kobayashi, Tatsuya, Okajima, Hodaka, Matsumoto, Kentaro, Hagiya, Yuichiro, Inoue, Keiji, Shuin, Taro, Nakajima, Motowo, Tanaka, Tohru, Ogura, Shun-ichiro
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114660/
https://ncbi.nlm.nih.gov/pubmed/27857072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36478
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