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CD45-mediated control of TCR tuning in naïve and memory CD8(+) T cells
Continuous contact with self-major histocompatibility complex (MHC) ligands is essential for survival of naïve T cells but not memory cells. This surprising finding implies that T cell subsets may vary in their relative T-cell receptor (TCR) sensitivity. Here we show that in CD8(+)T cells TCR sensit...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5114568/ https://ncbi.nlm.nih.gov/pubmed/27841348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13373 |
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