CD45-mediated control of TCR tuning in naïve and memory CD8(+) T cells

Continuous contact with self-major histocompatibility complex (MHC) ligands is essential for survival of naïve T cells but not memory cells. This surprising finding implies that T cell subsets may vary in their relative T-cell receptor (TCR) sensitivity. Here we show that in CD8(+)T cells TCR sensit...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Cho, Jae-Ho, Kim, Hee-Ok, Ju, Young-Jun, Kye, Yoon-Chul, Lee, Gil-Woo, Lee, Sung-Woo, Yun, Cheol-Heui, Bottini, Nunzio, Webster, Kylie, Goodnow, Christopher C., Surh, Charles D., King, Cecile, Sprent, Jonathan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114568/
https://ncbi.nlm.nih.gov/pubmed/27841348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13373
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi