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Epigenetic engineering reveals a balance between histone modifications and transcription in kinetochore maintenance
Centromeres consist of specialized centrochromatin containing CENP-A nucleosomes intermingled with H3 nucleosomes carrying transcription-associated modifications. We have designed a novel synthetic biology ‘in situ epistasis' analysis in which H3 dimethylated on lysine 4 (H3K4me2) demethylase L...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5114538/ https://ncbi.nlm.nih.gov/pubmed/27841270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13334 |
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