A phase I pharmacokinetic and safety study of cabazitaxel in adult cancer patients with normal and impaired renal function

PURPOSE: Limited data are available on cabazitaxel pharmacokinetics in patients with renal impairment. This open-label, multicenter study assessed cabazitaxel in patients with advanced solid tumors and normal or impaired renal function. METHODS: Cohorts A (normal renal function: creatinine clearance...

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Détails bibliographiques
Publié dans:Cancer Chemother Pharmacol
Auteurs principaux: Azaro, Analía, Rodón, Jordi, Machiels, Jean-Pascal, Rottey, Sylvie, Damian, Silvia, Baird, Richard, Garcia-Corbacho, Javier, Mathijssen, Ron H. J., Clot, Pierre-François, Wack, Claudine, Shen, Liji, de Jonge, Maja J. A.
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2016
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114328/
https://ncbi.nlm.nih.gov/pubmed/27796539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-016-3175-7
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