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Unveiling changes in the landscape of patient populations in cancer early drug development

The introduction of new Molecularly Targeted Agents (MTA) has changed the landscape in Early Drug Development (EDD) over the last two decades, leading to an improvement in clinical trial design. Previous Phase 1 (Ph1) studies with cytotoxics focused on safety objectives, only recruiting heavily pre-...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Hierro, Cinta, Azaro, Analía, Argilés, Guillem, Elez, Elena, Gómez, Patricia, Carles, Joan, Rodon, Jordi
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355170/
https://ncbi.nlm.nih.gov/pubmed/27835915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13258
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