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Unveiling changes in the landscape of patient populations in cancer early drug development

The introduction of new Molecularly Targeted Agents (MTA) has changed the landscape in Early Drug Development (EDD) over the last two decades, leading to an improvement in clinical trial design. Previous Phase 1 (Ph1) studies with cytotoxics focused on safety objectives, only recruiting heavily pre-...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Hierro, Cinta, Azaro, Analía, Argilés, Guillem, Elez, Elena, Gómez, Patricia, Carles, Joan, Rodon, Jordi
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355170/
https://ncbi.nlm.nih.gov/pubmed/27835915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13258
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