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Microglial phospholipase D4 deficiency influences myelination during brain development
Phospholipase D4 (PLD4) is expressed in activated microglia that transiently appear in white matter during postnatal brain development. Previous knockdown experiments using cultured microglia showed PLD4 involvement in phagocytosis and proliferation. To elucidate the role of PLD4 in vivo, PLD4-defic...
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| izdano v: | Proc Jpn Acad Ser B Phys Biol Sci |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Japan Academy
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5114292/ https://ncbi.nlm.nih.gov/pubmed/27477458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2183/pjab.92.237 |
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