Microglial phospholipase D4 deficiency influences myelination during brain development

Phospholipase D4 (PLD4) is expressed in activated microglia that transiently appear in white matter during postnatal brain development. Previous knockdown experiments using cultured microglia showed PLD4 involvement in phagocytosis and proliferation. To elucidate the role of PLD4 in vivo, PLD4-defic...

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Bibliographic Details
Published in:Proc Jpn Acad Ser B Phys Biol Sci
Main Authors: CHIBA, Terumasa, OTANI, Yoshinori, YAMAGUCHI, Yoshihide, ISHIBASHI, Tomoko, HAYASHI, Akiko, TANAKA, Kenji F., YAMAZAKI, Maya, SAKIMURA, Kenji, BABA, Hiroko
Format: Artigo
Language:Inglês
Published: The Japan Academy 2016
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114292/
https://ncbi.nlm.nih.gov/pubmed/27477458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2183/pjab.92.237
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