Microglial phospholipase D4 deficiency influences myelination during brain development

Phospholipase D4 (PLD4) is expressed in activated microglia that transiently appear in white matter during postnatal brain development. Previous knockdown experiments using cultured microglia showed PLD4 involvement in phagocytosis and proliferation. To elucidate the role of PLD4 in vivo, PLD4-defic...

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Veröffentlicht in:Proc Jpn Acad Ser B Phys Biol Sci
Hauptverfasser: CHIBA, Terumasa, OTANI, Yoshinori, YAMAGUCHI, Yoshihide, ISHIBASHI, Tomoko, HAYASHI, Akiko, TANAKA, Kenji F., YAMAZAKI, Maya, SAKIMURA, Kenji, BABA, Hiroko
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Japan Academy 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114292/
https://ncbi.nlm.nih.gov/pubmed/27477458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2183/pjab.92.237
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