Microglial phospholipase D4 deficiency influences myelination during brain development

Phospholipase D4 (PLD4) is expressed in activated microglia that transiently appear in white matter during postnatal brain development. Previous knockdown experiments using cultured microglia showed PLD4 involvement in phagocytosis and proliferation. To elucidate the role of PLD4 in vivo, PLD4-defic...

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Foilsithe in:Proc Jpn Acad Ser B Phys Biol Sci
Main Authors: CHIBA, Terumasa, OTANI, Yoshinori, YAMAGUCHI, Yoshihide, ISHIBASHI, Tomoko, HAYASHI, Akiko, TANAKA, Kenji F., YAMAZAKI, Maya, SAKIMURA, Kenji, BABA, Hiroko
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Japan Academy 2016
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Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114292/
https://ncbi.nlm.nih.gov/pubmed/27477458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2183/pjab.92.237
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