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Upregulation of large myelin protein zero leads to Charcot–Marie–Tooth disease-like neuropathy in mice

Charcot–Marie–Tooth (CMT) disease is a hereditary neuropathy mainly caused by gene mutation of peripheral myelin proteins including myelin protein zero (P0, MPZ). Large myelin protein zero (L-MPZ) is an isoform of P0 that contains an extended polypeptide synthesized by translational readthrough at t...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Otani, Yoshinori, Ohno, Nobuhiko, Cui, Jingjing, Yamaguchi, Yoshihide, Baba, Hiroko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070019/
https://ncbi.nlm.nih.gov/pubmed/32170207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0854-z
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