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Imaging Spatiotemporal Activities of ZAP-70 in Live T Cells Using a FRET-based Biosensor
The zeta-chain-associated protein kinase 70 kDa (ZAP-70), a member of the spleen tyrosine kinase (Syk) family, plays an essential role in early T cell receptor (TCR) signaling. Defects in ZAP-70 lead to impaired thymocyte development and peripheral T cell activation. To better understand its activat...
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| Udgivet i: | Ann Biomed Eng |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5114152/ https://ncbi.nlm.nih.gov/pubmed/27384937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-016-1683-6 |
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