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New Structural Data Reveal the Motion of Carrier Proteins in Nonribosomal Peptide Synthesis

The nonribosomal peptide synthetases (NRPSs) are one of the most promising resources for the production of new bioactive molecules. The mechanism of NRPS catalysis is based around sequential catalytic domains: these are organized into modules, where each module selects, modifies, and incorporates an...

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Détails bibliographiques
Publié dans:Angew Chem Int Ed Engl
Auteurs principaux: Kittilä, Tiia, Mollo, Aurelio, Charkoudian, Louise K., Cryle, Max J.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113783/
https://ncbi.nlm.nih.gov/pubmed/27435901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201602614
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