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New Structural Data Reveal the Motion of Carrier Proteins in Nonribosomal Peptide Synthesis

The nonribosomal peptide synthetases (NRPSs) are one of the most promising resources for the production of new bioactive molecules. The mechanism of NRPS catalysis is based around sequential catalytic domains: these are organized into modules, where each module selects, modifies, and incorporates an...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Kittilä, Tiia, Mollo, Aurelio, Charkoudian, Louise K., Cryle, Max J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113783/
https://ncbi.nlm.nih.gov/pubmed/27435901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201602614
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