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Structural basis of mRNA cap recognition by Dcp1–Dcp2
Removal of the 5′ cap on mRNA by the decapping enzyme Dcp2 is a critical step in 5′-to-3′ mRNA decay. Understanding the structural basis of Dcp2 activity has been a significant challenge because Dcp2 is dynamic, with weak affinity for cap substrate. Here we present a 2.6-Å-resolution crystal structu...
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| Publicado en: | Nat Struct Mol Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5113729/ https://ncbi.nlm.nih.gov/pubmed/27694842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3301 |
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