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Adenosine Selectively Depletes Alloreactive T Cells to Prevent GVHD While Conserving Immunity to Viruses and Leukemia

Selective depletion (SD) of alloreactive T cells from allogeneic hematopoeitic stem cell transplants to prevent graft-versus-host disease (GVHD) without compromising immune reconstitution and antitumor responses remains a challenge. Here, we demonstrate a novel SD strategy whereby alloreacting T cel...

詳細記述

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書誌詳細
出版年:Mol Ther
主要な著者: Whitehill, Greg D, Amarnath, Shoba, Muranski, Pawel, Keyvanfar, Keyvan, Battiwalla, Minoo, Barrett, Austin J., Chinnassamy, Dhanalakshmi
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113112/
https://ncbi.nlm.nih.gov/pubmed/27401140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.147
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