Reduction of Minimal Residual Disease in Pediatric B-lineage Acute Lymphoblastic Leukemia by an Fc-optimized CD19 Antibody

Prognosis of primary refractory and relapsed pediatric B-lineage acute lymphoblastic leukemia (ALL) is very poor. Relapse rates significantly correlate with persistent minimal residual disease (MRD). In MRD, favorable effector-target ratios prevail and thus this situation might be optimally suited f...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Seidel, Ursula Jördis Eva, Schlegel, Patrick, Grosse-Hovest, Ludger, Hofmann, Martin, Aulwurm, Steffen, Pyz, Elwira, Schuster, Friedhelm R, Meisel, Roland, Ebinger, Martin, Feuchtinger, Tobias, Teltschik, Heiko-Manuel, Witte, Kai-Erik, Schwarze, Carl-Philipp, Rammensee, Hans-Georg, Handgretinger, Rupert, Jung, Gundram, Lang, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5113107/
https://ncbi.nlm.nih.gov/pubmed/27380762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.141
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