Pediatric posttransplant relapsed/refractory B-precursor acute lymphoblastic leukemia shows durable remission by therapy with the T-cell engaging bispecific antibody blinatumomab

We report on posttransplant relapsed pediatric patients with B-precursor acute lymphoblastic leukemia with no further standard of care therapy who were treated with the T-cell engaging CD19/CD3-bispecific single-chain antibody construct blinatumomab on a compassionate use basis. Blast load was asses...

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Autori principali: Schlegel, Patrick, Lang, Peter, Zugmaier, Gerhard, Ebinger, Martin, Kreyenberg, Hermann, Witte, Kai-Erik, Feucht, Judith, Pfeiffer, Matthias, Teltschik, Heiko-Manuel, Kyzirakos, Christina, Feuchtinger, Tobias, Handgretinger, Rupert
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2014
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077083/
https://ncbi.nlm.nih.gov/pubmed/24727818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.100073
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