Differentially Methylated DNA Regions in Monozygotic Twin Pairs Discordant for Rheumatoid Arthritis: An Epigenome-Wide Study

OBJECTIVES: In an explorative epigenome-wide association study (EWAS) to search for gene independent, differentially methylated DNA positions and regions (DMRs) associated with rheumatoid arthritis (RA) by studying monozygotic (MZ) twin pairs discordant for RA. METHODS: Genomic DNA was isolated from...

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Pubblicato in:Front Immunol
Autori principali: Svendsen, Anders J., Gervin, Kristina, Lyle, Robert, Christiansen, Lene, Kyvik, Kirsten, Junker, Peter, Nielsen, Christian, Houen, Gunnar, Tan, Qihua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2016
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112246/
https://ncbi.nlm.nih.gov/pubmed/27909437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00510
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