Differentially Methylated DNA Regions in Monozygotic Twin Pairs Discordant for Rheumatoid Arthritis: An Epigenome-Wide Study

OBJECTIVES: In an explorative epigenome-wide association study (EWAS) to search for gene independent, differentially methylated DNA positions and regions (DMRs) associated with rheumatoid arthritis (RA) by studying monozygotic (MZ) twin pairs discordant for RA. METHODS: Genomic DNA was isolated from...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Svendsen, Anders J., Gervin, Kristina, Lyle, Robert, Christiansen, Lene, Kyvik, Kirsten, Junker, Peter, Nielsen, Christian, Houen, Gunnar, Tan, Qihua
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112246/
https://ncbi.nlm.nih.gov/pubmed/27909437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00510
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