Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis

Monozygotic or ‘identical’ twins have been widely studied to dissect the relative contributions of genetics and environment in human diseases. In multiple sclerosis (MS), an autoimmune demyelinating disease and common cause of neurodegeneration and disability in young adults, disease discordance in...

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Autori principali: Baranzini, Sergio E., Mudge, Joann, van Velkinburgh, Jennifer C., Khankhanian, Pouya, Khrebtukova, Irina, Miller, Neil A., Zhang, Lu, Farmer, Andrew D., Bell, Callum J., Kim, Ryan W., May, Gregory D., Woodward, Jimmy E., Caillier, Stacy J., McElroy, Joseph P., Gomez, Refujia, Pando, Marcelo J., Clendenen, Leonda E., Ganusova, Elena E., Schilkey, Faye D., Ramaraj, Thiruvarangan, Khan, Omar A., Huntley, Jim J., Luo, Shujun, Kwok, Pui-yan, Wu, Thomas D., Schroth, Gary P., Oksenberg, Jorge R., Hauser, Stephen L., Kingsmore, Stephen F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862593/
https://ncbi.nlm.nih.gov/pubmed/20428171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08990
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