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SNP imputation bias reduces effect size determination
Imputation is a commonly used technique that exploits linkage disequilibrium to infer missing genotypes in genetic datasets, using a well-characterized reference population. While there is agreement that the reference population has to match the ethnicity of the query dataset, it is common practice...
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Publicado no: | Front Genet |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Media S.A.
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4321633/ https://ncbi.nlm.nih.gov/pubmed/25709616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00030 |
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