How imputation can mitigate SNP ascertainment Bias

BACKGROUND: Population genetic studies based on genotyped single nucleotide polymorphisms (SNPs) are influenced by a non-random selection of the SNPs included in the used genotyping arrays. The resulting bias in the estimation of allele frequency spectra and population genetics parameters like heter...

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Bibliographic Details
Published in:BMC Genomics
Main Authors: Geibel, Johannes, Reimer, Christian, Pook, Torsten, Weigend, Steffen, Weigend, Annett, Simianer, Henner
Format: Artigo
Language:Inglês
Published: BioMed Central 2021
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8114708/
https://ncbi.nlm.nih.gov/pubmed/33980139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-021-07663-6
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