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How array design creates SNP ascertainment bias

Single nucleotide polymorphisms (SNPs), genotyped with arrays, have become a widely used marker type in population genetic analyses over the last 10 years. However, compared to whole genome re-sequencing data, arrays are known to lack a substantial proportion of globally rare variants and tend to be...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Geibel, Johannes, Reimer, Christian, Weigend, Steffen, Weigend, Annett, Pook, Torsten, Simianer, Henner
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8009414/
https://ncbi.nlm.nih.gov/pubmed/33784304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0245178
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