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On the Origin of Rheumatoid Arthritis: The Impact of Environment and Genes—A Population Based Twin Study

BACKGROUND: Rheumatoid arthritis (RA) is an autoimmune disease with a complex origin. Previous studies have reported heritability estimates on RA at about 60%. Only 16% of the genetic background of the disease has been disclosed so far. The purpose of the present investigation was to provide an opti...

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Autors principals: Svendsen, Anders J., Kyvik, Kirsten O., Houen, Gunnar, Junker, Peter, Christensen, Kaare, Christiansen, Lene, Nielsen, Christian, Skytthe, Axel, Hjelmborg, Jacob V.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585362/
https://ncbi.nlm.nih.gov/pubmed/23468964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057304
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