RAC1 GTPase promotes the survival of breast cancer cells in response to hyper-fractionated radiation treatment

Radiation therapy is a staple approach for cancer treatment, whereas radioresistance of cancer cells remains a substantial clinical problem. In response to ionizing radiation (IR) induced DNA-damage, cancer cells can sustain/activate pro-survival signaling pathways, leading to apoptotic resistance a...

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Bibliografski detalji
Izdano u:Oncogene
Glavni autori: Hein, Ashley L., Post, Carl M., Sheinin, Yuri M., Lakshmanan, Imayavaramban, Natarajan, Amarnath, Enke, Charles A., Batra, Surinder K., Ouellette, Michel M., Yan, Ying
Format: Artigo
Jezik:Inglês
Izdano: 2016
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112160/
https://ncbi.nlm.nih.gov/pubmed/27181206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.163
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