Inhibition of RAC1 GTPase sensitizes pancreatic cancer cells to γ-irradiation

Radiation therapy is a staple treatment for pancreatic cancer. However, owing to the intrinsic radioresistance of pancreatic cancer cells, radiation therapy often fails to increase survival of pancreatic cancer patients. Radiation impedes cancer cells by inducing DNA damage, which can activate cell...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Yan, Ying, Hein, Ashley L., Etekpo, Asserewou, Burchett, Katrina M., Lin, Chi, Enke, Charles A., Batra, Surinder K., Cowan, Kenneth H., Ouellette, Michel M.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
Matèries:
Priority Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279370/
https://ncbi.nlm.nih.gov/pubmed/25344910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.2500
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