Microphthalmia-Associated Transcription Factor Suppresses Invasion by Reducing Intracellular GTP Pools

Melanoma progression is associated with increased invasion and, often, decreased levels of microphthalmia-associated transcription factor (MITF). Accordingly, downregulation of MITF induces invasion in melanoma cells, however little is known about the underlying mechanisms. Here, we report for the f...

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Bibliographic Details
Published in:Oncogene
Main Authors: Bianchi-Smiraglia, Anna, Bagati, Archis, Fink, Emily E., Moparthy, Sudha, Wawrzyniak, Joseph A., Marvin, Elizabeth K., Battaglia, Sebastiano, Jowdy, Peter, Kolesnikova, Maria, Foley, Colleen E., Berman, Albert E., Kozlova, Nadezhda I., Lipchick, Brittany C., Paul-Rosner, Leslie M., Bshara, Wiam, Ackroy, Jeff, Shewach, Donna S., Nikiforov, Mikhail A.
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112150/
https://ncbi.nlm.nih.gov/pubmed/27181209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.178
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