Pharmacological targeting of guanosine monophosphate synthase suppresses melanoma cell invasion and tumorigenicity

Malignant melanoma possesses one of the highest metastatic potentials among human cancers. Acquisition of invasive phenotypes is a prerequisite for melanoma metastases. Elucidation of the molecular mechanisms underlying melanoma invasion will greatly enhance the design of novel agents for melanoma t...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Bianchi-Smiraglia, A, Wawrzyniak, J A, Bagati, A, Marvin, E K, Ackroyd, J, Moparthy, S, Bshara, W, Fink, E E, Foley, C E, Morozevich, G E, Berman, A E, Shewach, D S, Nikiforov, M A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648332/
https://ncbi.nlm.nih.gov/pubmed/25909885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.47
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