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Optogenetic activation of dopamine neurons in the ventral tegmental area induces reanimation from general anesthesia

Dopamine (DA) promotes wakefulness, and DA transporter inhibitors such as dextroamphetamine and methylphenidate are effective for increasing arousal and inducing reanimation, or active emergence from general anesthesia. DA neurons in the ventral tegmental area (VTA) are involved in reward processing...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Taylor, Norman E., Van Dort, Christa J., Kenny, Jonathan D., Pei, JunZhu, Guidera, Jennifer A., Vlasov, Ksenia Y., Lee, Justin T., Boyden, Edward S., Brown, Emery N., Solt, Ken
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111696/
https://ncbi.nlm.nih.gov/pubmed/27791160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1614340113
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