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Activation of GABAergic Neurons in the Rostromedial Tegmental Nucleus and Other Brainstem Regions Promotes Sedation and Facilitates Sevoflurane Anesthesia in Mice
Many general anesthetics potentiate GABA(A) receptors but their neuroanatomic sites of action are less clear. GABAergic neurons in the rostromedial tegmental nucleus (RMTg) send inhibitory projections to multiple arousal-promoting nuclei, but the role of these neurons in modulating consciousness is...
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Опубликовано в: : | Anesth Analg |
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Главные авторы: | , , , , , , , , , |
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
2021
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7969415/ https://ncbi.nlm.nih.gov/pubmed/33560660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000005387 |
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