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Activation of GABAergic Neurons in the Rostromedial Tegmental Nucleus and Other Brainstem Regions Promotes Sedation and Facilitates Sevoflurane Anesthesia in Mice

Many general anesthetics potentiate GABA(A) receptors but their neuroanatomic sites of action are less clear. GABAergic neurons in the rostromedial tegmental nucleus (RMTg) send inhibitory projections to multiple arousal-promoting nuclei, but the role of these neurons in modulating consciousness is...

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Detalhes bibliográficos
Publicado no:Anesth Analg
Main Authors: Vlasov, Ksenia, Pei, JunZhu, Nehs, Christa J., Guidera, Jennifer A., Zhang, Edlyn R., Kenny, Jonathan D., Houle, Timothy T., Brenner, Gary J., Taylor, Norman E., Solt, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7969415/
https://ncbi.nlm.nih.gov/pubmed/33560660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000005387
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