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Optogenetic activation of dopamine neurons in the ventral tegmental area induces reanimation from general anesthesia

Dopamine (DA) promotes wakefulness, and DA transporter inhibitors such as dextroamphetamine and methylphenidate are effective for increasing arousal and inducing reanimation, or active emergence from general anesthesia. DA neurons in the ventral tegmental area (VTA) are involved in reward processing...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Taylor, Norman E., Van Dort, Christa J., Kenny, Jonathan D., Pei, JunZhu, Guidera, Jennifer A., Vlasov, Ksenia Y., Lee, Justin T., Boyden, Edward S., Brown, Emery N., Solt, Ken
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111696/
https://ncbi.nlm.nih.gov/pubmed/27791160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1614340113
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