Laminin targeting of a peripheral nerve-highlighting peptide enables degenerated nerve visualization

Target-blind activity-based screening of molecular libraries is often used to develop first-generation compounds, but subsequent target identification is rate-limiting to developing improved agents with higher specific affinity and lower off-target binding. A fluorescently labeled nerve-binding pept...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Glasgow, Heather L., Whitney, Michael A., Gross, Larry A., Friedman, Beth, Adams, Stephen R., Crisp, Jessica L., Hussain, Timon, Frei, Andreas P., Novy, Karel, Wollscheid, Bernd, Nguyen, Quyen T., Tsien, Roger Y.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2016
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111686/
https://ncbi.nlm.nih.gov/pubmed/27791138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1611642113
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