Laminin targeting of a peripheral nerve-highlighting peptide enables degenerated nerve visualization

Target-blind activity-based screening of molecular libraries is often used to develop first-generation compounds, but subsequent target identification is rate-limiting to developing improved agents with higher specific affinity and lower off-target binding. A fluorescently labeled nerve-binding pept...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Glasgow, Heather L., Whitney, Michael A., Gross, Larry A., Friedman, Beth, Adams, Stephen R., Crisp, Jessica L., Hussain, Timon, Frei, Andreas P., Novy, Karel, Wollscheid, Bernd, Nguyen, Quyen T., Tsien, Roger Y.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2016
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111686/
https://ncbi.nlm.nih.gov/pubmed/27791138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1611642113
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