Structural flexibility at a major conserved antibody target on hepatitis C virus E2 antigen

Hepatitis C virus (HCV) is a major cause of liver disease, affecting over 2% of the world’s population. The HCV envelope glycoproteins E1 and E2 mediate viral entry, with E2 being the main target of neutralizing antibody responses. Structural investigations of E2 have produced templates for vaccine...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kong, Leopold, Lee, David E., Kadam, Rameshwar U., Liu, Tong, Giang, Erick, Nieusma, Travis, Garces, Fernando, Tzarum, Netanel, Woods, Virgil L., Ward, Andrew B., Li, Sheng, Wilson, Ian A., Law, Mansun
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111675/
https://ncbi.nlm.nih.gov/pubmed/27791120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609780113
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