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Hepatitis C virus E2 envelope glycoprotein core structure

Hepatitis C virus (HCV), a Hepacivirus, is a major cause of viral hepatitis, liver cirrhosis and hepatocellular carcinoma. HCV envelope glycoproteins E1 and E2 mediate fusion and entry into host cells and are the primary targets of the humoral immune response. The crystal structure of the E2 core bo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kong, Leopold, Giang, Erick, Nieusma, Travis, Kadam, Rameshwar U., Cogburn, Kristin E., Hua, Yuanzi, Dai, Xiaoping, Stanfield, Robyn L., Burton, Dennis R., Ward, Andrew B., Wilson, Ian A., Law, Mansun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954638/
https://ncbi.nlm.nih.gov/pubmed/24288331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1243876
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