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Differential growth triggers mechanical feedback that elevates Hippo signaling

Mechanical stress can influence cell proliferation in vitro, but whether it makes a significant contribution to growth control in vivo, and how it is modulated and experienced by cells within developing tissues, has remained unclear. Here we report that differential growth reduces cytoskeletal tensi...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Pan, Yuanwang, Heemskerk, Idse, Ibar, Consuelo, Shraiman, Boris I., Irvine, Kenneth D.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5111668/
https://ncbi.nlm.nih.gov/pubmed/27791172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1615012113
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